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Administrative data

Description of key information

acute oral toxicity, rat (M/f), gavage, > 8000 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
8 000 mg/kg bw

Additional information

The analogue test item was tested for acute oral toxicity (Huntsman, 1980). Male and female rats were gavaged at different doses up to 8000 mg/kg bw. Under the experimental conditions the LD50 > 8000 mg/kg bw.

Based on the read across considerations the same results apply to Acid Black 164.

Justification for classification or non-classification

According to the CLP Regulation (EC n. 1272/2008), table 3.1.1, Acute toxicity hazard categories and acute toxicity estimates (ATE) defining the respective categories:

For Acute toxicity oral route:

Category 1: ATE <= 5 mg/kg bw

Category 2: 5 < ATE <= 50 mg/kg bw

Category 3: 50 < ATE <= 300 mg/kg bw

Category 4: 300 < ATE <= 2000 mg/kg bw

The LD50 of the test substance was determined to be 8000 mg/kg bw , which is outside the above criteria. Therefore, the test substance is not classified for Acute toxicity by oral exposure.