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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

acute oral toxicity, rat (M/f), gavage, > 8000 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
8 000 mg/kg bw

Additional information

The analogue test item was tested for acute oral toxicity (Huntsman, 1980). Male and female rats were gavaged at different doses up to 8000 mg/kg bw. Under the experimental conditions the LD50 > 8000 mg/kg bw.

Based on the read across considerations the same results apply to Acid Black 164.

Justification for classification or non-classification

According to the CLP Regulation (EC n. 1272/2008), table 3.1.1, Acute toxicity hazard categories and acute toxicity estimates (ATE) defining the respective categories:

For Acute toxicity oral route:

Category 1: ATE <= 5 mg/kg bw

Category 2: 5 < ATE <= 50 mg/kg bw

Category 3: 50 < ATE <= 300 mg/kg bw

Category 4: 300 < ATE <= 2000 mg/kg bw

The LD50 of the test substance was determined to be 8000 mg/kg bw , which is outside the above criteria. Therefore, the test substance is not classified for Acute toxicity by oral exposure.