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EC number: 249-535-3 | CAS number: 29253-36-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
In a valid GLP test according to OECD test method 310 (Ready Biodegradability - CO2 in Sealed Vessels, Headspace Test), 60% biodegradation was observed after 23 d within a 12-days window. GC-analysis demonstrated >99% elimination of the test substance after 16 days.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
In a MITI II test (OECD 302 B, 28 d) using a concentration of 30 mg/L of MIPN, only poor biodegradation was observed with a low BOD of about 12 % (NITE 2011a/2010). However, GC-analysis suggested significant primary degradation under test conditions (removal of the pristine test substance of about 93 %).
In a valid follow-up study applying the OECD method 310 (Ready Biodegradability - CO2 in Sealed Vessels, Headspace Test), biodegradation of 60 % was reached after 23 d within a 12-days window, hence just failing the 10-days window (Fiebig/NOACK 2013). GC-analysis demonstrated >99% elimination of the original substance after 16 days.
Gafik
The NITE study has been disregarded, because a negative-selective stress usually imposed on the inoculum in these Japanese investigations favours the loss of indigenous potent microorganisms carrying special properties of decomposition.
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