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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 Feb 2013 - 20 Feb 2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
not specified
Type of method:
HPLC method
Key result
Type:
log Pow
Partition coefficient:
> 5.7
Temp.:
23 °C
Remarks on result:
other: pH NA as not aqueous
Details on results:
Log Pow >5.7 at 23oC

All soluble parts of the test item OLEYL PALMITAMIDE eluted after the reference item Triphenylamine. Therefore only the retention time of Triphenylamine was measured.

  

Item

Retention time (minutes)

Log Pow

Reference item - Triphenylamine

3.5

5.7

OLEYL PALMITAMIDE

after 5 mins

> 5.7

 

When applying the retention time of the reference item Triphenylamine, the following partition coefficient can be reported:

 

Log Pow(OLEYL PALMITAMIDE) > 5.7

 

 

Annotations:

 

The pH value could not be determined as the test item was solvated in tetrahydrofuran. pH value is only defined for aqueous solutions.

Test temperature: 23°C

Conclusions:
Log Pow > 5.7 at 23oC

Description of key information

Log Kow: > 5.7 at 23°C

Key value for chemical safety assessment

Additional information

A log Kow value of > 5.7 at 23°C was determined using the HPLC method according to EU Method A.8.