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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23 Jul 2012 to 21 Sep 2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
equivalent or similar to
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
not specified
Type of method:
other: Grain-Watson estimation
Temp.:
20 °C
Vapour pressure:
< 0 Pa

The experimentally determined vapour pressure of the test item Oleyl Palmitamide, CAS-No. 16260 -09-6 at 20°C is not in the recommended range of 1 to 1000 mbar for DSC-measurements.  

 

Therefore an estimation procedure in accordance with the test method OECD guideline 104 “OECD Guideline For The Testing Of Chemicals, adopted by the council on 23 March 2006, Vapour Pressure” ANNEX Estimation Method newest version (Robert S. Boethling, Donald Mackay, Handbook of Property Estimation Methods for Chemicals, Lewis Publishers, year of publication 2000, Cap. 3 – Vapour Pressure, Grain-Watson Method, p. 53 – 65) was used. This method is applied for vapour pressures between 103and 10-7mbar.

This deviates from the older version published in OECD Guideline 104. It was used due to the differentiation between solids and liquids, which results in a more precise estimate.

 

Please note:

Substances with a higher vapour pressure need to be assessed more critically, eg. concerning the release of toxic substances, than those with a lower vapour pressure. For this reason, the calculation above is based on the theoretically instead of the experimentally determined vapour pressure.  

 

Description of key information

< 8.3E-05 Pa at 20 °C

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

A vapour pressure of 8.3E-05 Pa at 20 °C was obtained using an estimation procedure in accordance with the test method OECD guideline 104 (Grain-Watson estimation).