Fatty alcohols, C12-18 (even numbered), manuf. of, destn. residues

Endpoint summary

Additional information

Study data for Behenyl Bottoms, characterized as alcohol C18-22, distillation residues (CAS No. 1160164-88-4),where available, has been evaluated and considered for assessment of alcohols, C12 -18, distn. residues, in a read-across approach (for details plaese refer to the attached read-across report). Reliable data for Behenyl Bottoms was available for short-term toxicity to invertebrates, short-term toxicity to fish, toxicity to algae, and toxicity to microorganisms. No reliable long-term data for fish or invertebrates were available. In a conservative approach the most sensitive study result related to each endpoint was chosen as Key and is summarized below. There was no reliable long-term toxicity data for fish, invertebrates, aquatic plants and waivers apply to these endpoints.  

 

Short-term Toxicity to Fish

One reliable (Klimisch 1) short-term toxicity study for fish was available for Behenyl Bottoms. The short-term toxicity of Behenyl Bottoms to the fathead minnow (Pimephales promelas) was reported by Palmer (2009) in an OECD 203 guideline and GLP compliant study. Fish were exposed to the test substance in measured concentrations for 96 hours, resulting in a 96-hr LC50 of >100 mg/L. 

Short-term Toxicity to Invertebrates

One reliable (Klimisch 1) short-term toxicity study for invertebrates was available for Behenyl Bottoms. The short-term toxicity of Behenyl Bottoms to Daphnia magnawas reported by Palmer et al. (2009) in an OECD 202 guideline and GLP compliant study. Daphnia were exposed to the test substance in measured concentrations for 48 hours, resulting in a 48-hr EC50 of >100 mg/L. 

 

Long-term Toxicity to Fish and Invertebrates

Mid-range chain length alcohols (C11-C13) and longer chain length alcohols (C14 -C15) are reported to have a very high biodegradability (readily biodegradable with extremely high removal in environmentally relevant concentrations; OECD SIDS Long Chain Alcohols, 2006). Longest chain alcohols (>C16) also exhibit significant biodegradation. Thus, long-term effects by Alcohols, C12-18, distn. residues on aquatic organisms are not expected due to quick removal under environmentally relevant conditions, which means long-term exposure to aquatic organisms is unlikely.

Toxicity to Aquatic Algae

One reliable (Klimisch 1) toxicity study for aquatic algae was available for Behenyl Bottoms. The toxicity of Behenyl Bottoms toPseudokirchnerella subcapitatawas reported by Cartee et al., (2009) in an OECD 201 guideline and GLP compliant study. Algae was exposed to the test substance in measured concentrations for 72 hours, resulting in a 72-hr EC50 of >100 mg/L, based on growth, cell density and yield. The 72-hr NOEC, based on growth rate, was >100 mg/L.

 

Toxicity to Microorganisms

One reliable (Klimisch 1) toxicity study for microorganisms was available for Behenyl Bottoms. The toxicity of Behenyl Bottoms to activated sludgewas reported by Schaefer & Twilly (2009) in an OECD 209 guideline and GLP compliant study. Activated sludge was exposed nominal concentrations of the test substance for 3 hours, resulting in a 3-hr LC50 of >1,000 mg/L, based respiration rate. 

 

In summary, study data for Behenyl Bottoms, characterized as alcohol C18-22, distillation residues (CAS No. 1160164-88-4), where available, has been evaluated and considered for assessment. Reliable data was available for short-term toxicity to invertebrates, short-term toxicity to fish, toxicity to algae, and toxicity to microorganisms. No reliable long-term data for fish or invertebrates were available. These data are used in a read-across approach in the assessment of alcohols, C12 -18, distn. residues.

Data requirements for long-term toxicity data for fish, invertebrates, and aquatic plants are waived.