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Dissociation constant

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Description of key information

pKa = 8.05 at 25 °C

Key value for chemical safety assessment

Additional information

The dissociation constant of 4'-hydroxyacetophenone was reported in an authoritative secondary source to be pKa = 8.05 at 25 °C. This attribute was supported by accepted calculation methods with a result of pKa = 8.05 at 25 °C in the SRC PhysProp database respectiveley 8.08 in a Sparc v4.5 calculation. Thus a dissociation constant of 8.05 at 25 °C is regarded to be reliable for 4'-hydroxyacetophenone.