Registration Dossier
Registration Dossier
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EC number: 264-172-0 | CAS number: 63450-43-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Toxicity of several derivatives of aromatic amines
- Author:
- Silaev AA et.al.
- Year:
- 1 996
- Bibliographic source:
- Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology.Volume/page/year: (10),36,1996
- Reference Type:
- review article or handbook
- Title:
- RTECS Number : DB4979000
- Author:
- RTECS Database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):-Silaev AA et.al.; Toxicity of several derivatives of aromatic amines; MTPEEI Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology.Volume/page/year: (10),36,1996
- Reference Type:
- other: Authoritative data base
- Title:
- ACToR no: 350108
- Author:
- ACToR Database
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource):- Silaev AA et.al.; Toxicity of several derivatives of aromatic amines; Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (10), Pg. 36, 1996.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Standard acute method
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium 3-methylsulphanilate
- EC Number:
- 264-172-0
- EC Name:
- Sodium 3-methylsulphanilate
- Cas Number:
- 63450-43-1
- Molecular formula:
- C7H9NO3S.Na
- IUPAC Name:
- sodium 3-methylsulphanilate
- Details on test material:
- - Name of test material: sodium 3-methylsulphanilate
- Substance type:organic
- Physical state:solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- other: LD
- Effect level:
- > 15 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The acute oral median lethal dose (LD) of sodium 3-methylsulphanilate in rat was found to be >15000 mg/kg of body weight. Acute toxicity of sodium 3-methylsulphanilate to rat by the oral route indicates that the substance does not exhibits acute toxicity by the oral route.
- Executive summary:
The acute oral median lethal dose (LD) of sodium 3-methylsulphanilate in rat was found to be >15000 mg/kg of body weight. Acute toxicity of sodium 3-methylsulphanilate to rat by the oral route indicates that the substance does not exhibits acute toxicity by the oral route.
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