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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Administrative data

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
no
GLP compliance:
yes
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
cascade impaction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution
Mass median aerodynamic diameter:
3.09 µm
Geometric standard deviation:
2.65
Key result
Percentile:
D10
Mean:
> 0.32 - < 0.83 µm
St. dev.:
0
Remarks on result:
other: st dev was set to 0, based on no data
Key result
Percentile:
D25
Mean:
ca. 4.4 µm
St. dev.:
0
Remarks on result:
other: st dev was set to 0, based on no data
Conclusions:
The particle size distribution was determined in the the context of the study for acute inhalation.

Description of key information

Additional information