Registration Dossier
Registration Dossier
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EC number: 204-388-4 | CAS number: 120-35-4
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: testing method performed according to OECD107
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 3-amino-4-methoxybenzanilide
- EC Number:
- 204-388-4
- EC Name:
- 3-amino-4-methoxybenzanilide
- Cas Number:
- 120-35-4
- Molecular formula:
- C14H14N2O2
- IUPAC Name:
- 3-amino-4-methoxy-N-phenylbenzamide
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.08
- Temp.:
- 23 °C
- pH:
- ca. 7
Any other information on results incl. tables
Table 1: Results in detail
| determ. no. | stock solution [ml] | water[ml] | test substanceconc. in n-octanol phase[mg/l] | test substance conc. in water phase[mg/l] | log Pow |
| A1 | 5 | 10 | 831,6 | 6,8 | 2,09 |
| A2 | 5 | 10 | 824,5 | 6,6 | 2,10 |
| B1 | 10 | 10 | 836,8 | 6,9 | 2,08 |
| B2 | 10 | 10 | 828,7 | 7,1 | 2,07 |
| C1 | 20 | 10 | 838,0 | 7,3 | 2,06 |
| C2 | 20 | 10 | 833,5 | 7,3 | 2,06 |
| mean | --- | --- | --- | --- | 2,08 |
Stock solution: 829,0 mg/I
Cone. of filtered stock solution: 873,3 mg/I (= 105 % recovery rate)
Applicant's summary and conclusion
- Conclusions:
- Due to the partition coefficient n-octanol-water of 2.08 bioaccumulation is not expected.
- Executive summary:
The partition coefficient n-octanol/water was determined according to OECD 107 as 2.08 at 23°C.
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