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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

In a weight of evidence based on QSAR modelling an EC50 of 0.018 mg/l is estimated for Daphnia magna. 

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.018 mg/L

Additional information

QSAR calculations are available for the QSAR tool ECOSAR V. 1.00 and Catalogic 5.11.16 for the test substance. QSAR modelling revealed an EC50 value for the ECOSAR class : Epoxide, mono a specific toxicity of EC50: 0.041 mg/l for 48 h exposure and for baseline toxicity an EC50 of 0.018 mg/l in Daphnia. The substances are covered by the applicability domaine of the QSAR tools for baseline toxicity.

Modelling with Catalogic 5.11.16 revealed an EC50 of for Daphnia magna < 0.047 mg/l. The substance is covered by the applicability domaine of the tool.