Registration Dossier
Registration Dossier
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EC number: 204-817-5 | CAS number: 126-98-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (21 d) 6.33 mg/L (OECD 211)
NOEC (21 d) 2.2 mg/L (OECD 211)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.2 mg/L
Additional information
According to ECHA guidance on information requirements and chemical safety assessment Chapter R.10: Characterisation of dose [concentration]-response for environment, two long-term results (such as EC10 or NOECs) from species representing two trophic levels (fish and/or Daphnia and/or algae) permit an assessment factor of 50 to be applied when calculating the freshwater PNEC.
The availability of a GLP study with analytical monitoring, which describes long-term toxicity to Daphnia magna (Ministry of Environment, Japan, 2000), allows that report to be used in conjunction with the long-term toxicity data from algae (Environment Agency of Japan, 2000) during PNEC calculation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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