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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 January 2010 – 01 April 2010
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study has been performed according to OECD and EC guidelines and according to GLP principles.

Data source

Reference Type:
study report
Report date:

Materials and methods

Test guideline
according to guideline
EU Method A.16 (Relative Self-Ignition Temperature for Solids)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EC Number:
EC Name:
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cas Number:
Molecular formula:
7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Details on test material:
- Name of test material (as cited in study report): 7-ADCA
- Molecular formula: C8H10N2O3S
- Molecular weight: 214.2
- Substance type: White powder
- Physical state: solid
- Analytical purity: 99.0%
- Impurities: -
- Isomers composition: -
- Purity test date: -
- Lot/batch No: D212013
- Expiration date of the lot/batch: 28 February 2011 (retest date)
- Stability under test conditions: Stable
- Storage condition of test material: In refrigerator (2-8°C) in the dark
- Other: Test substance handling: -

Results and discussion

Relative self-ignition temperature (solids)
Remarks on result:
other: the test substance is considered ‘not self-ignitable’.

Any other information on results incl. tables

An exothermic effect of the test substance by self-heating was observed at an oven temperature of 195°C. During this effect the test substance reached a temperature of 245°C. According to the guideline, a test substance is self-ignitable when the sample temperature reaches 400°C by self-heating. Based on this, the test substance is considered ‘not self-ignitable’.


After the experiment, the test substance had turned into acharred residue and was still in the test cube. It indicated that the test substance had decomposed and/or reacted during the experiment.

Applicant's summary and conclusion

The self-ignition temperature of 7-ADCA was determined using a temperature programmed laboratory oven, a stainless steel wire mesh cube, NiCr/NiAl thermocouples and a temperature recording device.

Based on the results obtained the test substance is considered ‘not self-ignitable’.