Registration Dossier
Registration Dossier
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EC number: 261-819-9 | CAS number: 59587-44-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects on aquatic microorganisms up to the limit of water solubility, read across.
Key value for chemical safety assessment
Additional information
Data on the toxicity of 2-ethylhexanol nonanoate (CAS 59587-44-9)
to aquatic microorganisms are not available. The assessment was
therefore based on studies conducted with the structurally similar
substance Octyl octanoate (CAS 2306-88-9) as part of a read across
approach, which is in accordance with Regulation (EC) No. 1907/2006,
Annex XI, 1.5. Further justification is given within the overall summary
chapter 6.1 and within the analogu juestification section 13.
The toxicity of octyl octanoate (CAS No. 2306-88-9) to activated sludge
microorganisms was tested according to OECD Guideline 209 (Hammer,
2013). Activated sludge was exposed to the test substance in a static
system for 3 hours, at nominal concentrations of 1000, 500, 250, 125 and
62.5 mg/L. No toxicity was observed at any of the tested concentrations,
and the EC10 was determined to be > 1000 mg/L. Thus, based on the above
mentioned result, and due to the structural and profile similarities of
the substances, as are explained with in the overall endpoint summary
6.1 it can be concluded that no toxicological effects on microroganisms
expected up to the limit of water solubility for 2-ethylhexanol
nonanoate (CAS 59587-44-9).
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