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Terrestrial toxicity tests are not available for 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD) and are being waived as

direct and indirect exposure of the soil compartment to TMCD is unlikely, and TMCD has a low log Pow and log Koc (<3.0) suggesting a low potentail to sorb to soils or bioaccumulate in terrestrial organisms. In the absence of toxicity data for soil organisms, the equilibrium partitioning method is being applied to assess the hazard to soil organisms and derive PNECs.