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Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96-h acute toxicity of the test item to Danio rerio was studied under semi-static conditins in a GLP study performed to OECD TG 203 and EC Method C.1. The 96-h LC50 was > 100 mg/L and the NOEC was 100 mg/L based on nominal concentrations.

Key value for chemical safety assessment

Additional information

One study is available. In this study, performed under GLP according to OECD TG 203 and EC Method C.2, juvenile Zebra fish (Danio rerio; groups of seven animals) were exposed to the test item at concentrations of 0 or 100 mg/L for 96 hours at a temperature of approximately 21 °C under semi-static test conditions.In the analyzed test medium samples from the start of the renewal periods, the measured test item concentration (sum of peaks) ranged between 89 and 93% of the nominal value. This shows the correct preparation of the test medium. At the end of the renewal periods, the measured test item concentration (sum of peaks) ranged between 80 and 85% of the nominal value. Given that the toxicity cannot be attributed to a single component or a mixture of components, but to the test item as a whole, the results were based on the nominal test concentration of 100 mg/L.

In the control and at the test concentration of 100 mg/L no mortality or other visible abnormalities were determined at the test fish during the test period of 96 hours. The 96 -h LC50 was > 100 mg/L and the NOEC was 100 mg/L.