Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Follows a recognised guideline and performed to GLP standards.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Water solubilityopen allclose all
Water solubility:
193 g/L
Temp.:
20 °C
pH:
8.8
Water solubility:
297 g/L
Temp.:
20 °C
pH:
8.9
Water solubility:
701 g/L
Temp.:
20 °C
pH:
9
Details on results:
Preliminary test - Preliminary testing indicated that on using a loading rate of 100 g trisodium 6,6',6"-(1,3,5-triazine-2,4,6-triyltriimino)trihexanoate per litre of glass double-distilled water, a sample concentration of 98.1 g test material per litre of solution was obtained. The pH of this solution was 7.5. As the loading rate and sample concentration numbers were very similar, extra method development work was then carried out; the results for this extra work suggested that the sample concentration was dependent on the loading rate.

Definitive test: The concentrations (g/l) of trisodium 6,6',6"-(1,3,5-triazine-2,4,6-triyltriimino)trihexanoate in the sample solution is shown in the table below.

Any other information on results incl. tables

Concentration of trisodium 6,6',6"-(1,3,5-triazine-2,4,6-triyltriimino)trihexanoate in sample solution:

 Sample number Time shaken at 30 C (Hours)  Time equilibrated at 20 C (Hours)  Concentration (g/l)  Solution pH 
19.25  193  8.8 
19.25  297  8.9 
19.25  701  9.0 

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): other: water solubility is loading rate dependent
No precise value for water solubility could be determined: results obatined from sample analyses showed a dependence on loading rate. This may suggest formation of colloidal solutions or micro-emulsions rather than true dissolution.