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Description of key information

GLP Study according to international standard ISO 1183 as referenced in the EU testing guideline A.3.
General Physical Chemistry, Schering AG, Berlin, Study report No. NC59EY10 (APC 86/99), dated 1999-11-05.
Result: relative density at 20°C is 1.254.

Key value for chemical safety assessment

Relative density at 20C:

Additional information


Measurements of the relative density were performed with a pyknometer (50 mL capacity) equipped with a side-arm overflow capillary and a thermometer graduated in 0.1 °C according to the international standard ISO 1183.

n-hexan was used as immersion liquid.

To remove all air from the specimen, the pyknometer partially filled with the specimen and the immersion liquid was evacuated in a desiccator. After breaking the vacuum the pyknometer was removed in a thermostated bath and exactly filled to the limit of capacity with the immersion liquid.

The temperature was kept constant at 20 °C ± 0.01°C using an ultrathermostat

The following equation was used for calculation:       ds= (ms x dIL)/(m1-m2)                                             

ds =  density of the specimen (g/mL)

ms=  mass of the specimen (g)

m1=  mass of the liquid required to fill the pyknometer (g)

m2=  mass of liquid required to fill the pyknometer containing the specimen (g)

dIL=  density of the immersion liquid (g/mL)


Averaging the results of two experiments gives a relative density at 20 °C (related to water at 4°C) of 1.245.

Physical state of the test substance: solid