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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
yes
Remarks:
deviations were considered as uncritical
Principles of method if other than guideline:
Deviations:
1) The temperature in the main study was higher than stated in the guideline. Because the algae showed a normal growth, this deviation was stated as uncritical.
2) The temperature in the reference study was higher than stated in the guideline. Because the algae showed a normal growth, this deviation was stated as uncritical.
GLP compliance:
yes (incl. QA statement)
Analytical monitoring:
yes
Vehicle:
no
Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Reference substance (positive control):
yes
Remarks:
potassium dichromate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
6.5 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
LOEC
Effect conc.:
17.1 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 33 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate
Validity criteria fulfilled:
yes
Conclusions:
EC50 (72 h) > 33 mg/L
NOEC (72 h) = 6.5 mg/L
Executive summary:

EC50 > 33 mg/L, no acute aquatic hazard, category 1 classification

Description of key information

NOEC(72 h) = 6.5 mg/L		
LOEC(72 h) = 17.1 mg/L		
EC50(72 h) > 33 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
33 mg/L
EC10 or NOEC for freshwater algae:
6.5 mg/L

Additional information