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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
yes
Remarks:
Temperature for the main and the referenz study higher than stated in guideline
Principles of method if other than guideline:
The temperature for the main study and the referenz study was higher than stated in guideline. As no immobility occured during the test, this deviation was stated as uncritical.
GLP compliance:
yes (incl. certificate)
Analytical monitoring:
yes
Vehicle:
no
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h
Reference substance (positive control):
yes
Remarks:
potassium dichromate
Duration:
24 h
Dose descriptor:
NOEC
Effect conc.:
32.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
> 32.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
24 h
Dose descriptor:
EC100
Effect conc.:
> 32.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
32.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 32.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
> 32.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

 Nominal concentration in mg/L     pH    O2concentrationin mg/L
0h  48h  0h  48h
7.7  7.6  8.3  8.0
100  7.8  7.6  8.1  7.9 
Validity criteria fulfilled:
yes
Conclusions:
EC50 (48 h) > 32.7 mg/L
NOEC (48 h) = 32.7 mg/L
Executive summary:

EC50 > 32.7 mg/L, no acute aquatic hazard, category 1 classification

Description of key information

NOEC(24h) = 32.7 mg/L		
EC50(24h) > 32.7 mg/L
EC100(24h) > 32.7 mg/L
NOEC(48h) = 32.7 mg/L
EC50(48h) > 32.7 mg/L
EC100(48h) > 32.7 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
32.7 mg/L

Additional information