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EC number: 604-569-1 | CAS number: 147126-62-3
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14.08.2006 to 03.11.2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Menthyloxathiolane
- IUPAC Name:
- Menthyloxathiolane
- Reference substance name:
- (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
- EC Number:
- 604-569-1
- Cas Number:
- 147126-62-3
- Molecular formula:
- C14H24O4S
- IUPAC Name:
- (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
- Test material form:
- solid: compact
Constituent 1
Constituent 2
Study design
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- The activated sludge used for this study was washed by centrifugation and the supernatant liquid phase was decanted. The solid material was re-suspended in tap water and again centrifuged. This procedure was repeated twice. An aliquot of the final sludge suspension was weighed, dried
and the ratio of
wet sludge to its dry weight was determined. Based on this
ratio, calculated aliquots of washed sludge suspension, corresponding
to 1.5 g dry material per litre were mixed with test
water (see 6.5) and then aerated until use.
The washed activated sludge was feed and aerated according
to the test guideline and used one day later for the experiment. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 51 mg/L
- Details on study design:
- Surrounding Type: Climatic chamber
Temperature: 22 °C
Light Conditions: Darkness
pH-Value of Test Solutions: 7.6 (measured at the start of the test) 7.7- 7.9 (measured at the end of the test)
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 44
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 51
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Conclusions:
- Based on ThODNH4. the degradation rate of menthyloxathiolane reached 44% (mean) after 14 days of incubation and 51% (mean) after 28 days of incubation. The degradation rate of menthyloxathiolane did not reach 60 % within the 10-day window and after 28 days of incubation. Therefore,
menthyloxathiolane is not considered to be readily biodegradable.
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