Registration Dossier
Registration Dossier
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EC number: 939-689-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Acutely toxic to aquatic organisms.
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Reaction mass of bis(2-hydroxyethanaminium) sulfite and 2-(methylamino)ethanol - oxosulfane oxide (1:1) is soluble in water and dissociates to 2 -(methylamino)ethanol, (2- hydroxyethyl)ammonium and sulphite ions.
Since no studies on the aquatic toxicity of the substance are available, study reports and published literature about the toxic effects of 2-aminoethanol (CAS 141-43-5), 2 -(methylamino)ethanol (CAS 109 -83 -1) and substances of the sulphite category (e.g. sodium sulphite, CAS 7757-83-7) have been consulted alternatively.
Guideline studies from toxicity testing with the dissociation products and read-across substances are available for every endpoint, respectively. Fish was found to be the least sensitive organism with LC50 values > 100 mg/L retrieved from toxicity testing with 2-aminoethanol as well as with 2 -(methylamino)ethanol and the sulphite category members.
Effect concentrations for aquatic invertebrates were found to be in the range of 10 to 100 mg/L for 2-aminoethanol (i.e. EC50 = 65 mg/L), 2 -(methylamino)ethanol (EC50 = 33 mg/l) and disodium disulphite (i.e. EC50 = 74.9 mg SO32-/L), respectively.
Aquatic plants were found to be the most sensitive organisms with a detected ErC50 of 2.8 mg/L and a NOErC of 1 mg/L with the dissociation product 2-aminoethanol.
Effect concentrations for 2 -(methylamino)ethanol were in the range of 10 to 100 mg/L (i.e. ErC 50 = 28.1) .
Effect concentrations for sodium sulphite were in the range of 10 to 100 mg/L (i.e. ErC 50 = 36.8 mg SO32-/L; NOErC = 28 mg/L).
Data on the long-term toxicity of the dissociation products are available with all but one NOEC being above 1 mg/L. Chronic testing of 2-aminoethanol on Daphnia magna according to OECD guideline 211 resulted in a NOEC of 0.85 mg/L.
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