Registration Dossier
Registration Dossier
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EC number: 200-683-7 | CAS number: 68-26-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-Guideline study according to OECD
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Retinol
- EC Number:
- 200-683-7
- EC Name:
- Retinol
- Cas Number:
- 68-26-8
- Molecular formula:
- C20H30O
- IUPAC Name:
- (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
- Details on test material:
- - Name of test material (as cited in study report): Retinol crystalline
- Lot/batch No.: 090-04-06
- Analytical purity: 93.9 %
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Inoculum: Activated sludge from laboratory wastewater plant treating municipal sewage.
Concentration of activated sludge in the test assay: 30 mg/l (dry substance). - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 24 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
-
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes
- Toxicity control: yes
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 80 - 90
- Sampling time:
- 28 d
- Details on results:
- Kinetic of test substance (in %):
= 8 after 5 day(s)
= 13 after 7 day(s)
= 52 after 17 day(s)
= 66 after 24 day(s)
= 81 after 28 day(s)
Ten day window failed
BOD5 / COD results
- Results with reference substance:
- Kinetic of control substance (in %):
= 1 after 3 day(s)
= 70 after 10 day(s)
Applicant's summary and conclusion
- Interpretation of results:
- other: biodegradable
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