Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Patty's Industrial Hygiene and|Toxicology, 3rd edtn., Vol. 2C
Author:
Clayton, G.D., Clayton, F.E.
Year:
1982
Bibliographic source:
Wiley, New York 1982, S. 4688

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Methylpentynol
EC Number:
201-055-5
EC Name:
Methylpentynol
Cas Number:
77-75-8
Molecular formula:
C6H10O
IUPAC Name:
3-methylpent-1-yn-3-ol
Specific details on test material used for the study:
No details about the study design available.

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
800 mg/kg bw

Any other information on results incl. tables

liver and nephrotoxic effects

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria