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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

A valid activated Sludge Respiration Inhibition Test (OECD 209) according to GLP is abvailable.  The EC10was found to be 540 mg/l and the EC50 wasdetermined to be > 1000 mg/l. 

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
540 mg/L

Additional information

One study investigating the toxicity of Propanamide, 2-hydroxy-N,N-dimethyl- to aquatic microorganisms is available. The study was conducted under static conditions and according to GLP and OECD guideline 209 using domestic, non-adapted activated sludge as inoculum (BASF, 2012). Nominal test substance concentrations between 62.5 and 1000 mg/L were applied. The following effect concentrations for respiration inhibition were observed compared to the control after a test period of 3 h : EC10 (3h) is determined to be 540 mg/L, the EC50: > 1000 mg/l.