Registration Dossier
Registration Dossier
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EC number: 298-842-9 | CAS number: 93839-71-5
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 471 (Bacterial Reverse Mutation Assay)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- 4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
- EC Number:
- 298-842-9
- EC Name:
- 4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
- Cas Number:
- 93839-71-5
- Molecular formula:
- C13H20N2O.C2H4O2
- IUPAC Name:
- 4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
Constituent 1
Results and discussion
Test resultsopen allclose all
- Species / strain:
- S. typhimurium TA 98
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Species / strain:
- S. typhimurium TA 100
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Remarks on result:
- other: all strains/cell types tested
- Remarks:
- Migrated from field 'Test system'.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
Based on the results of this study it is concluded that NA-872 AMINOACETAT is not mutagenie in the Salmonella)yphimurium reverse mutation assay.
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