4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate

Acute Toxicity: oral

Administrative data

Endpoint:

acute toxicity: oral

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1983

Report date:

1983

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method B.1 tris (Acute Oral Toxicity - Acute Toxic Class Method)

Deviations:

not specified

GLP compliance:

yes

Test type:

acute toxic class method

Test material

Test material information

Constituent 1

Reference substance name:

4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate

EC Number:

298-842-9

EC Name:

4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate

Cas Number:

93839-71-5

Molecular formula:

C13H20N2O.C2H4O2

IUPAC Name:

4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate

Test animals

Species:

rat

Strain:

other: Chbb: THOM

Sex:

male/female

Administration / exposure

Route of administration:

oral: gavage

Vehicle:

other: bidestilliertes Wasser mit 0,1 % Zusatz Tween 80

Doses:

2000; 3160 and 5000 mg/kg

No. of animals per sex per dose:

5male and 5 female per dose

Control animals:

not specified

Results and discussion

Effect levels

Effect levels 1

Sex:

male

Dose descriptor:

LD50

Effect level:

>= 3 160 - <= 5 000 mg/kg bw

Based on:

test mat.

Effect levels 2

Sex:

female

Dose descriptor:

LD50

Effect level:

>= 3 665.3 mg/kg bw

Based on:

test mat.

Applicant's summary and conclusion

Interpretation of results:

practically nontoxic

Remarks:

Migrated information Criteria used for interpretation of results: EU