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EC number: 276-594-2 | CAS number: 72361-35-4
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
LC50 > 1,000 mg/kg for Eisenia fetida based on read across (OECD 207)
Key value for chemical safety assessment
Additional information
As no valid study is available for assessing the toxicity to soil macroorganisms of Triisotridecyl benzene-1,2,4-tricarboxylate (CAS No. 72361-35-4), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related category member 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) was conducted. The read across is justified due to a) the structural similarity of the category members and b) similar physico-chemical properties resulting in a similar environmental fate and ecotoxicity profile.Further justification is given within the endpoint summary 6.1 and within the category justification section 13.
The study with 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) was performed under GLP and according to EU method C.8 using the earthworm Eisenia foetida as test organism (Scholz, 1994). This limit test performed at a concentration of 1,000 mg/kg dry soil was conducted using artificial soil. No mortality was observed in the control and the treatment during the test period of 14 days. Hence, the 14 d-LC 50 is determined to be > 1,000 mg/kg dry soil.
Thus, based on the above mentioned results, and due to the structural similarities and a consistent ecotoxicological/environmental fate profile of the substances, as are explained with in the overall endpoint summary in IUCLID chapter 6.1, it can be concluded that no acute toxicity of Triisotridecyl benzene-1,2,4-tricarboxylate (CAS No. 72361-35-4) to soil macroorganisms is expected.
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