Registration Dossier
Registration Dossier
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EC number: 202-257-6 | CAS number: 93-55-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature is available. There are no information on the testing procedure nor on the substance composition.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- RTECS Database
- Year:
- 2 016
- Bibliographic source:
- RTECS Database
- Reference Type:
- review article or handbook
- Title:
- Prehled Prumyslove Toxikologie.
- Author:
- Marhold, J.
- Year:
- 1 986
- Bibliographic source:
- Organicke Latky. Prague, Czechoslovakia, Avicenum. 291
Materials and methods
- Principles of method if other than guideline:
- Data from secondary sources; Standard Draize Test.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Propiophenone
- IUPAC Name:
- Propiophenone
Constituent 1
Test animals
- Species:
- rabbit
Test system
- Amount / concentration applied:
- 500 mg
- Observation period:
- 24 hours
Results and discussion
In vivo
Results
- Remarks on result:
- other: Mild irritation
- Irritant / corrosive response data:
- Mild irritant
Applicant's summary and conclusion
- Conclusions:
- Mild irritant
- Executive summary:
Data from secondary sources; no further details about testing method and procedures are available. The substance was applied on the skin of rabbits and after 24 hours the skin resulted mildly irrititated.
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