Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 202-257-6 | CAS number: 93-55-0
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Monographs on fragrance raw materials: Acetophenone.
- Author:
- Opdyke D.L.J
- Year:
- 1 973
- Bibliographic source:
- Food and Cosmetics Toxicology, 11: 99-100
- Reference Type:
- other: reference mentioned into the monograph
- Title:
- -
- Author:
- Kligman, A. M.
- Year:
- 1 971
- Bibliographic source:
- Report to RIFM, 9 June.
- Reference Type:
- other: reference mentioned into the monograph
- Title:
- The identification of contact allergens by human assay. III.The maximization test. A procedure for screening and rating contact sensitizers.
- Author:
- Kligman, A. M.
- Year:
- 1 966
- Bibliographic source:
- J. invest. Derm. 47, 393.
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- not specified
- Principles of method if other than guideline:
- Maximization test (Kligman, 1966).
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-phenylethanone
- IUPAC Name:
- 1-phenylethanone
Constituent 1
Method
- Type of population:
- not specified
Results and discussion
- Results of examinations:
- A maximization test on acetophenone at 2 % concentration produced no reaction.
Applicant's summary and conclusion
- Conclusions:
- A maximization test (Kligman, 1966) on acetophenone at 2 % concentration produced no reaction (Kligman, 1971).
- Executive summary:
A maximization test (Kligman, 1966) on acetophenone at 2 % concentration produced no reaction (Kligman, 1971).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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