Registration Dossier
Registration Dossier
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EC number: 202-257-6 | CAS number: 93-55-0
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Information about dissociation constant are available from literature.
Chlorination of propiophenone in alkaline aqueous solution leads to formation of α-hydroxypropiophenone as the first detectable intermediate; this undergoes slower oxidation to aromatic acids without any accumulation of further intermediates. From the rates of the initial chlorination authors have been able to determine the pKa value as 17.56 ± 0.51.
REFERENCE
Guthrie J.P. and Cossar J. (1990), "Canadian Journal of Chemistry", 68, "2060 - 2069".
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