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Diss Factsheets
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EC number: 248-948-6 | CAS number: 28299-41-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The half-life for the photodegradation of ditolyl ether by reaction with hydroxyl radicals in air is estimated to be 0.62 days or 14.8 hours as estimated with AOPWIN (v1.91).
The substance does not contain any hydrolysable functional groups. No abiotic degradation of ditolyl ether was observed. Consequently ditolylether is assumed to be stable at 50 °C and pH 4, 7 and 9.
Ditolyl ether is not readily biodegradable when using unadapted inoculum from a wastewater treatment plant treating predominantly domestic sewage as shown in a Manometric Respirometry Test (OECD 301 D, 2 % after 28 days).
Ditolyl ether was not inherently biodegradable using activated sludge, mixture of domestic and industrial STP, in a modified MITI test (II) (OECD 302 C, 3 % after 28 days).
In an OECD 309 test performed with a mixture of the 6 isomers, five isomers were found to be degraded with DT50 values below 40°C at 12°C. The 2,2 -isomer however showed a longer half life of 63 days at 12°C.
The BCF of ditolyl ether was calculated from the read across substance diphenyl ether (CAS 101-84-8), using the data provided by the study of DOW Chemical Company, 1973, which were supported by valid QSAR estimation using EPIWIN. The read across BCF was determined to be 982. However, a final SEv decision has been issued by ECHA, requesting a BCF study depending on the outcome of the OECD 309 simulation study in water.
An adsorption coefficient (log Koc) 4.0 was determined at pH 6. The result can be expected to be equal at 25 °C.
The Henry's Law Constant was calculated by HENRYWIN (v.3.20) to be 4.864 Pa m3/mol at 25°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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