Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
3.1 µg/L
Assessment factor:
1 000
PNEC freshwater (intermittent releases):
31 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.31 µg/L
Assessment factor:
10 000

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
17.1 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
1.7 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
1.6 µg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

The following data for aquatic toxicity and environmental fate are available:

  • Biodegradability: the test item is not readily biodegradable
  • Log Kow = -1.21
  • Toxicity to fish: LC50-96h = 20 mg/L
  • Short term toxicity to aquatic invertebrates: 48h-EC50 = 3.1 mg/L
  • Toxicity to aquatic algae: ErC50-72h= 30 mg/L & ErC10-72h= 18 mg/L

Regarding these data,4-methyl-3-thiosemicarbazideshould be classified as follows: 

  • According to the Directive 67/548/EC:R51/53
  • According to CLP: chronic toxicity category 2