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Physical & Chemical properties

Partition coefficient

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Description of key information

The Log Kow for 4-methylthiosemicarbazide is calculated to be -1.21.Considering this value,4-methylthiosemicarbazide has a low potential for bioaccumulation.

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.21

Additional information

The Log Kow for 4-methylthiosemicarbazide is calculated to be -1.21.Considering this value,4-methylthiosemicarbazide has a low potential for bioaccumulation.

According to the Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance (ECHA, 2008), the impact of errors on model predictions for a log Kow value below 1 is usually less critical. Moreover, the value estimated is outside the applicability range of the reverse phase HPLC method (OECD GL 117) and very closed to the lowest value of the applicability range of the shake flask method (OECD GL 107). Therefore, it is considered that an experimental study is not needed.