Registration Dossier
Registration Dossier
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EC number: 416-900-5 | CAS number: 79723-02-7 TMAP
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: expert statement
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Theoretical assessment taking all currrently available relevant information into account, based on the REACH Guidance: Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7c Endpoint specific guidance. Since this is a the0retical assessment, the Klimisch value cannot be 1.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Guidance for the implementation of REACH: Guidance on information requirements and chemical safety assessment. Chapter R.7c: Endpoint specific guidance, European Chemical Agency, May 2008.
- GLP compliance:
- no
Test material
- Reference substance name:
- Tetramethylammonium hydrogen phthalate
- EC Number:
- 416-900-5
- EC Name:
- Tetramethylammonium hydrogen phthalate
- Cas Number:
- 79723-02-7
- Molecular formula:
- C12H17NO4
- IUPAC Name:
- tetramethylazanium 2-carboxybenzoate
- Test material form:
- solid: crystalline
Constituent 1
Results and discussion
Main ADME results
- Type:
- absorption
- Results:
- For risk assessment purposes, 50% is used for oral and dermal absorption, 100% for inhalation absorption.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): other: low bioaccumulation potential based on theoretical assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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