Registration Dossier

Administrative data

Endpoint:
toxicity to terrestrial arthropods
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
terrestrial toxicity by ECOSAR Version 1.10
Author:
ECOSAR Version 1.10
Year:
2012
Bibliographic source:
ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: modelling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-oxoglutaric acid
EC Number:
208-797-9
EC Name:
3-oxoglutaric acid
Cas Number:
542-05-2
Molecular formula:
C5H6O5
IUPAC Name:
3-oxopentanedioic acid
Details on test material:
- Name of test material : 3-oxoglutaric acid

Test organisms

Test organisms (species):
other: Earthworm

Study design

Total exposure duration:
14 d

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
7 113.764 other: mg/l
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Conclusions:
Toxicity to terrestrial arthropods (earthworm) for 3-oxoglutaric acid was estimated to be LC50 (14 days) : 7113.764 mg/L
Executive summary:

Toxicity to terrestrial arthropods (earthworm) for 3-oxoglutaric acid was estimated to be LC50 (14 days) : 7113.764 mg/L