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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
July 1975
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
according to
Guideline:
other: According to in-house SOP (A.11) devloped by CIBA comparable to today's standard guidlines
Deviations:
not specified
Principles of method if other than guideline:
Internal SOP followed.
GLP compliance:
no
Specific details on test material used for the study:
None
Analytical monitoring:
not specified
Vehicle:
not specified
Details on test solutions:
No data
Test organisms (species):
other: fish (Trout)
Details on test organisms:
None
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
No data
Hardness:
No data
Test temperature:
13 °C
pH:
7.9 to 8.0
Dissolved oxygen:
No data
Salinity:
No data
Nominal and measured concentrations:
Nominal concentrations: 2, 20 and 100 mg/l
Details on test conditions:
No data
Reference substance (positive control):
not specified
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
40 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
48 h
Dose descriptor:
LC100
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Details on results:
No mortality was seen at 2 mg/L, while 1 fish was found dead at 20 mg/L after 48 h exposure. At 100 mg/L, no exposed fish survived.
Results with reference substance (positive control):
None
Reported statistics and error estimates:
None
Validity criteria fulfilled:
not applicable
Conclusions:
The LC50 of the test substance was found to be 40 mg/L.
Executive summary:

The acute fish toxicity of FAT 21016/A was assessed in a study conducted accoding to a methodology similar to OECD 203. Groups of Rainbow trouts, each containing 8 fish, were exposed to the test concentrations of 2, 20 and 100 mg/L for 48 h. No mortality was seen at 2 mg/L, while 1 fish was found dead at 20 mg/L after 48 h exposure. At 100 mg/L, no exposed fish survived. Hence, the LC50 of the test substance was found to be 40 mg/L.

Description of key information

The acute toxicity of Acid Violet 109 was assesed in couple studies conducted using methodology similar to OECD Guideline 203. In the study considered as key, groups of Rainbow trouts, each containing 8 fish, were exposed to the test concentrations of 2, 20 and 100 mg/L for 48 h. No mortality was seen at 2 mg/L, while 1 fish was found dead at 20 mg/L after 48 h exposure. At 100 mg/L, no exposed fish survived. Hence, the LC50 of the test substance was found to be 40 mg/L. However, in a supporting study, no mortality was observed when groups of fish were exposed to FAT 20200/A at the test concentrations of 100, 200 and 1000 mg/L for 48 h. Hence, the TL50 of Acid Violet 109 in this study was found to be 1000 mg/l.

Key value for chemical safety assessment

LC50 for freshwater fish:
40 mg/L

Additional information