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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
Version / remarks:
adopted July 17, 1992
GLP compliance:
yes (incl. certificate)
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, non-adapted
Details on inoculum:
Non adapted activated suldge from the municipal sewage plant at D-31137 Hildesheim
Duration of test (contact time):
28 d
Initial conc.:
50 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Reference substance:
benzoic acid, sodium salt
Remarks:
45 mg/L
Test performance:
validity criteria were fulfilled
Key result
Parameter:
% degradation (O2 consumption)
Value:
10
Sampling time:
1 d
Remarks on result:
other: mean degradation
Key result
Parameter:
% degradation (O2 consumption)
Value:
60
Sampling time:
8 d
Remarks on result:
other: mean degradation
Key result
Parameter:
% degradation (O2 consumption)
Value:
99
Sampling time:
28 d
Remarks on result:
other: mean degradation
Results with reference substance:
In the toxicity control containing both test and reference item 87% degradation occured within 14 days. The functional control reached the pass level > 60% after 2 days and came to 100% after 28 days.
Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Conclusions:
The test item must be regarded as readily biodegradable in the 10-d-window.

Description of key information

The test item is readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

The ready biodegradability of the test item was assessed according to OECD guideline 301 F ( Dr. U. Noack-Laboratorien, 2007) using activated sludge and a non-adapted method during a 28 day incubation period. The test item reached the 10% level after 1 day and the pass level of 60% after 8 days. The mean biodegradation came to 99% after 28 days. In conclusion, the test item Crotonic acid must be regarded as readily biodegradable in the 10-d-window.

In addition, in a sewage waste water investigation (Hoechst AG, 1979) Crotonic acid showed a degradation of > 65%.