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Physical & Chemical properties

Particle size distribution (Granulometry)

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Administrative data

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012-10-11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
Qualifier:
according to guideline
Guideline:
other: ECHA Guidance chapter R. 7.1.14.2
Qualifier:
according to guideline
Guideline:
other: ISO 13320: Particle size analysis-Laser diffraction methods
GLP compliance:
yes
Type of method:
sieving
Type of distribution:
mass based distribution
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: DEBR 012553
Key result
Percentile:
D50
Remarks on result:
other: According to ECHA Guidance no further tests have to be performed, if there are no particles smaller than 100 µm.

The per cent by weight of the fine fraction < 2000 µm of the test item is 11.3% and does not contain any particles smaller than 125 µm.

Conclusions:
The fine fraction (< 2000 µm) of the test item Crotonic acid does not contain any particles smaller than 125 µm indicating that the test item has no respirable and inhalable particles.

Description of key information

Crotonic acid has no respirable and inhalable particles.

Additional information

Particle size distribution, determined by sieving (Consilab, 2012), indicated that the fine fraction (< 2000 µm) of the test item Crotonic acid does not contain any particles smaller than 125 µm indicating that the test item has no respirable and inhalable particles.