Registration Dossier
Registration Dossier
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EC number: 200-087-7 | CAS number: 51-28-5
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Data have been obtained from secondary source and the EPA databank. Different types of BCF are available.
The range of BCF- measured values is 3.0 to 16.
In another study BCF values of < 0.4-0.7 and < 3.7 were measured.
The BCF of 2,4-DNP in fish can be estimated tobe 0.56 using the equation log BCF = 1.02xlogKow - 1.82 to correct the BCF due to ionization in water and a value of 1.54 for log Kow.
Furthermore, no data were located on the biomagnification potential for dinitrophenols in predators that consume contaminated prey.
Key value for chemical safety assessment
Additional information
Estimated and experimental BCF values are available for 2,4-dinitrophenol.
The range of BCF measured is from 3.0 to 16. All test are conducted < 96 hours with Cyprinodon variegatus (fish) and Palaemonetes sp.(shrimp) in a static condition and in salt water (EPA databank).
Carps (Cyprinus carpio) were exposed over a 6 week incubation period at 2,4-dinitrophenol concentrations of 50 and 5 ug/L, respectively.
BCF values of < 0.4-0.7 and <3.7 were measured. According to a classification scheme these BCFs suggest that the potential for bioconcentration in aquatic organisms for 2,4 -dinitrophenol is low (SRC) (NITE; Chemical Risk Information Platform (CHRIP)).
Using the equation log BCF = 1.02xlogKow - 1.82 to correct the BCF due to ionization in water and a value of 1.54 for log Kow, the BCF of 2,4-DNP in fish can be estimated to be 0.56. Therefore, the concentration of 2,4-DNP in fish may be even lower than its concentration in water. (McCarty LS, Mackay D, Smith AD, et al. 1993).
Furthermore, bioconcentration of dinitrophenols from water to aquatic organisms and from soil to plants is not expected to be important. No data were located on the biomagnification potential for dinitrophenols in predators that consume contaminated prey (EPA 1986a; O’Connor et al. 1990).
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