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EC number: 920-632-9 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Test data is available on the acute toxicity of nickel slag and analogue substance (copper slag) to invertebrates. Lowest short-term toxicity value observed is greater than 100 mg/l.
Key value for chemical safety assessment
Additional information
A GLP OECD 202 guideline study (Simon, 2010) was performed on the analogue substance(copper slag) which assessed the effect of mesocosm water extracts of five slags on the immobilization ofDaphnia magna. The 48 h EC50 for copper slag in the range of 980 mg/l to >6250 mg/l were found. Typical slag samples have been tested with composition similar to the composition of nickel slag as outlined in IUCLID Section 1.2. Given lower release of metals from nickel slag comparing to copper slag in transformation/dissolution tests in standard media , value of acute toxicity for the nickel slag 48 h EC50 >100 mg/l shall be predicted.
Further OECD 202 guideline studies (Lebertz, 2007) and (Sauerwald and Weiss, 2004) investigated the toxicity of analogue substance (copper slag) onDaphnia magna in a 48h limit test. No toxic effects were observed at tested concentrations. EC50 and EC10 values of >1000 mg/L and > 100 g/l respectively were assessed. Typical slag samples have been tested with composition similar to the composition of nickel slag as outlined in IUCLID Section 1.2. Given lower release of metals from nickel slag comparing to copper slag in transformation/dissolution tests in standard media, value of acute toxicity for the nickel slag 48 h EC50 >100 mg/l shall be predicted.
The calculated classification of nickel slag via Toxic unit approach (Higher Tier Arche CLP Tool) resulted in No classification for the UVCB substance. Based on this result, the related criteria provided the estimated value for acute (short term) toxicity to aquatic invertebrate (see EU CLP Annex I Table 4.1.0): 48hr EC50 (for crustacea) >100 mg/l
Using a weight of evidence approach, the lowest short-term toxicity of nickel slag to invertebrates is greater than 100 mg/l which means No classification.
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