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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose:
reference to same study
Related information:
Composition 1
Reason / purpose:
reference to other study
Related information:
Composition 1
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes (incl. certificate)
Remarks:
Dept. of Health, UK
Type of method:
effusion method: vapour pressure balance
Test material information:
Composition 1
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
0.048 Pa

summary of the results:

 Run  Log10 [Vp(25°C)]
 1  -1.314
 2  -1.307
 3  -1.320
 4  -1.337
 5  -1.327
 6  -1.315
 7  -1.377
 8  -1.377
 9  -1.375
 10  -1.378

 mean

Vapour Pressure

 -1.323

0.048 Pa

 
Conclusions:
The vapour pressure of the active ingredient monoethanolamine thioglycolate has been determined to be 4.8 x 10exp-2 Pa at 25 °C.
Executive summary:

An attempt was made to determine the vapour pressure of the test material using the isoteniscope method. This attempt was unsuccessful, it appears that the water removed under the vaccuum conditions, then the remaining monoethanolamine thioglycolate decomposed without boiling. Therefore, the vapour pressure balance method were used to determine the Vp of monoethanolamine thioglycolate (active ingredient).

Description of key information

Ten measurements were performed according to OECD TG 104 (EU A4).

Key value for chemical safety assessment

Vapour pressure:
0.048 Pa
at the temperature of:
25 °C

Additional information

The sequence of ten runs was started after a sample of the test material had been held under vaccum for 215.75 h. Temperature and pressure readings were taken between 25 and 35°C with one hour dwell at 25 °C between the runs.