Registration Dossier
Registration Dossier
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EC number: 270-307-4 | CAS number: 68424-50-0
Endpoint summary
Administrative data
Description of key information
Not irritating for the skin
Not irritating for the eyes
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The potential of the test item to be irritant to the skin was investigated through an in vitro skin irritation study using a commercial reconstructed human epidermis (RhE) model named EPISKINTM and to cause corrosion/severe irritation by using the Bovine Corneal Opacity and Permeability (BCOP) assay. In both cases the result is negative. An in vivo study on the substance has not be performed, but in a wieght of evidence approach, the in vivo and ex vivo results for similar substances have been reported.
Justification for selection of skin irritation / corrosion endpoint:
GLP compliant with international guidelines
Justification for selection of eye irritation endpoint:
GLP compliant with international guidelines
Justification for classification or non-classification
No classification for skin and eye irritation is warranted under Regulation 1272/2008
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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