Registration Dossier
Registration Dossier
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Reaction mass of 2-{[3-(trimethoxysilyl)propyl]amino}ethanaminium chloride and 2-{benzyl[3-(trimethoxysilyl)propyl]amino}ethanaminium chloride and N-[2-(benzylamino)ethyl]-3-(trimethoxysilyl)propan-1-aminium chloride and N-[2-(dibenzylamino)ethyl]-3-(trimethoxysilyl)propan-1-aminium chloride and N-benzyl-2-{benzyl[3-(trimethoxysilyl)propyl]amino}ethanaminium chloride and N-benzyl-N-[2-(dibenzylamino)ethyl]-3-(trimethoxysilyl)propan-1-aminium chloride.
EC number: 700-961-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
One study is available, in which the short term toxicity of the substance towards the soil macroorganism Eisenia fetida was tested according to the OECD guideline 207 and GLP standards. The study did not show any effects to the organisms up to the highest tested concentration, resulting into a NOEC (14 d) of >= 1000 mg/kg dw and an LC50 (14 d) of > 1000 mg/kg dw (both nominal values).
Further testing for toxicity to terrestrial organisms is not considered necessary due to following reasons:
- PNECsoil has been calculated from PNEC aquatic (freshwater) on the basis of the equilibrium partitioning method; the risk characterisation ratio (RCR) based on PNECsoil is <1.
- No effects were observed in the study conducted with soil macroorganisms.
- In addition, testing for toxicity to terrestrial organisms is technically difficult in general due to condensation reactions at high test concentrations.
Overall, it is concluded that the risk characterisation conclusion is sufficiently conservative in respect of any uncertainties and therefore further testing is not considered necessary. Details on how the PNEC and the risk characterisation ratio have been derived can be found in IUCLID Section 6 and Chapters 7, 9 and 10 of the Chemical Safety Report.
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