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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

There is no fish toxicity test for "Reaction products of 3-methylbutanal and 3-methylbut-3-en-1-ol, distillation overheads, acid-treated, hydrogenated" available. Thus, the hazard assessment is based on both main components of the Reaction products. For 2H-Pyran, tetrahydro-4-methyl-2-(2-methylpropyl)- (CAS 13477-62-8; 30 -80% of the Reaction product) a study of a analog substance (CAS 16409-43-1) has been used. In that guideline study according to OECD 203 the acute toxicity of the substance to fish was determined. Test fish of the species Brachydanio rerio were exposed to the substance for 96 hours in a semi-static test system. At test termination a LC50 of 77.6 mg/L based on mean measured test substance concentrations was determined.

For the second main component 2H-pyran-4 -ol (CAS 63500-71-0; 10 -60% of reaction product) the toxicity to Oncorhychus mykiss was tested in a study performed according to OECD guideline 203. The test fish were exposed to 2H-pyran-4-ol for 96 hours. At test termination a LC50 354 mg/L was determined (Firmenich, 1989).

Based on both main components, the toxicity to fish of "Reaction products of 3-methylbutanal and 3-methylbut-3-en-1-ol, distillation overheads, acid-treated, hydrogenated" is considered to be 77.6 mg/L as a worst-case assumption.