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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

No toxic effects to fish up to the limit of water solubility (WS: < 0.05 mg/L; OECD 203).

Key value for chemical safety assessment

Additional information

In accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5 a read across to the structurally similar analogue substance 3,5,5-trimethylhexanoic acid mixed tetraesters with pentaerythritol and valeric acid (CAS 131459-39-7) was conductedtofulfil the data requirements according to Annex VII-IX of 2,2-bis[[(1-oxoisononyl)oxy]methyl]-1,3-propanediyl diisononanoate (93803-89-5) in regard to toxicity to fish.This read-across is justified in detail in the overall summary (IUCLID section 6.1) and within the analogue justification in IUCLID section 13. The substance consists of the same alcohol component(pentaerythritol) and similar fatty acid chain lengths as the target substance (C9iso for the target substance compared to C5-6 for the source substances, respectively).

The study with read-across3,5,5-trimethylhexanoic acid mixed tetraesters with pentaerythritol and valeric acid was conducted under semi-static conditions according to OECD 203 using rainbow trout as test organism (Wetton and Mullee, 1999). A nominal test concentration of 100 mg/L (prepared as WAF) was applied. No mortality and no signs of intoxication were observed after 96 h. Therefore, this study resulted in an EL50 of > 100 mg/L (nominal).

Based on the result from a structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5), which is characterized by a similar ecotoxicological profile and structure, it can be concluded that of 2,2-bis[[(1-oxoisononyl)oxy]methyl]-1,3-propanediyl diisononanoate will not exhibit acute toxic effects to fish up to the limit of water solubility.