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Environmental fate & pathways

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The biodegradation potential of TATD-CLE was evaluated by the prediction data generated by Biowin v.4.10 [1]. The screening criteria show that substance can be regarded as non readily biodegradable and as potentially persistent. Furthermore, this conclusion is supported by the evaluation of results obtained on the structural analogue Ceftaroline fosamil (EC:/; CAS: 400827-46-5).

No empirical bioaccumulation data are available for TATD-CLE, therefore also the BCF was estimated (using BCFBAF v.3.01 [1]). Considering the provisional data as well as the physical and chemical properties, TATD-CLE is not expected to be bioaccumulable.


[1] Biowin v.4.10 and BCFBAF v.3.01 are applications contained in the EpiSuite 4.1, the suite of physical/chemical property and environmental fate estimation programs developed by the EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC).