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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
Data is from ECOSAR version 1.11
Qualifier:
according to guideline
Guideline:
other: Modeling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Daphnia magna
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
21 d
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.495 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: ECOSAR v1.11
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 0.495 mg/l for aquatic invertebrate for 21 days of exposure duration.
Executive summary:

The long term toxicity on aquatic invertebrate was predicted for test substance by using ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the substance was estimated to be 0.495 mg/l for aquatic invertebrate for 21 days of exposure duration. By considering NOEC value, it is concluded that the test chemical can be considered as toxic to aquatic invertebrate and can be classified as aquatic chronic 2 per the CLP classification criteria.

Description of key information

Long term toxicity to aqatic invertebrate:

The long term toxicity on aquatic invertebrate was predicted for test substance by using ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the substance was estimated to be 0.495 mg/l for aquatic invertebrate for 21 days of exposure duration. By considering NOEC value, it is concluded that the test chemical can be considered as toxic to aquatic invertebrate and can be classified as aquatic chronic 2 per the CLP classification criteria.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.495 mg/L

Additional information

Long term toxicity to aqatic invertebrate:

The long term toxicity on aquatic invertebrate was predicted for test substance by using ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the substance was estimated to be 0.495 mg/l for aquatic invertebrate for 21 days of exposure duration. By considering NOEC value, it is concluded that the test chemical can be considered as toxic to aquatic invertebrate and can be classified as aquatic chronic 2 per the CLP classification criteria.