Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from ECOSAR version 1.11
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
Long term toxicity to fish was carried out according to the ECOSAR version 1.11
GLP compliance:
not specified
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
other: Fish
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
not specified
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
0.547 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: ECOSAR version 1.11
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be 0.547 mg/l for fish for 28 days of exposure duration
Executive summary:

The long term toxicity on fish was predicted for test substance by using EPI suite ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the test substance was estimated to be 0.547 mg/l for fish for 28 days of exposure duration. By considering the NOEC value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and can be classified aquatic chronic 2 as per the CLP classification criteria.

Description of key information

Long term toxicity to fish:

The long term toxicity on fish was predicted for test substance by using EPI suite ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the test substance was estimated to be 0.547 mg/l for fish for 28 days of exposure duration. By considering the NOEC value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and can be classified aquatic chronic 2 as per the CLP classification criteria.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
0.547 mg/L

Additional information

Long term toxicity to fish:

The long term toxicity on fish was predicted for test substance by using EPI suite ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the test substance was estimated to be 0.547 mg/l for fish for 28 days of exposure duration. By considering the NOEC value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and can be classified aquatic chronic 2 as per the CLP classification criteria.