Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Hydrolysis

On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be 9 days, at pH 7 and a temperature of 25-27°C, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is slowly hydrolysable in water.

Additional information

Hydrolysis

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the half-life of the test chemical. The studies are as mentioned below:

 

The neutral hydrolysis rate constant and half-life value of test chemical was determined at a pH 7. The neutral hydrolysis rate constant of test chemical was determined to be 0.0032/hr, respectively with a corresponding half-lives of 9 days at pH 7 and at a temperature of 25°C, respectively. Based on the half-life value, it is concluded that the test chemical is slow hydrolysable in water.

 

In an another study, the neutral hydrolysis rate constant and half-life value of test chemical was determined at a temperature of 27°C. Although half-life value of test chemical was not known, but test chemical was reported to undergo slow hydrolysis in water.

 

On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be 9 days, at pH 7 and a temperature of 25-27°C, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is slowly hydrolysable in water.