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Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bio-degradation in water by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
EC Number:
279-900-2
EC Name:
1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
Cas Number:
82104-74-3
Molecular formula:
C9H5NO2
IUPAC Name:
1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
Test material form:
solid: crystalline
Details on test material:
- Name of test material: 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile
- Molecular formula: C9H5NO2
- Substance type: Organic
- Physical state: Solid

Study design

Oxygen conditions:
other: modelling database
Inoculum or test system:
not specified
Duration of test (contact time):
15 d
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
test mat. analysis

Results and discussion

% Degradation
Parameter:
other: half life
Value:
50
Sampling time:
15 d
Remarks on result:
other: 15 days = 360 hrs
Details on results:
Half life = 15 days

Any other information on results incl. tables

Media

Half life

(days)

Percent in medium

Water

15 days

24%

 

Applicant's summary and conclusion

Interpretation of results:
readily biodegradable
Conclusions:
1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is 50% biodegradable in water in 15 days (half-life) indicating 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is readily biodegradable in water since the half life is less than the threshold of 60 days (to qualify the chemical as persistent)
Executive summary:

1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is 50% biodegradable in water in 15 days (half-life) indicating 1,3-dihydro-1-oxoisobenzofuran-5-carbonitrile is readily biodegradable in water since the half life is less than the threshold of 60 days (to qualify the chemical as persistent).

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